Mission: ISS is a free VR experience developed by Magnopus and published by Meta/Oculus in collaboration with NASA, the European Space Agency, and the Canadian Space Agency. Since its original release in March 2017 for Oculus Rift, it has transported nearly five million virtual astronauts to the International Space Station. It is a non-profit initiative: no one is paid when you download it. It is Emmy-nominated, and the Meta Quest version holds a 4.1-star rating from over 1,800 reviews.

The experience was built from authentic NASA ISS models and refined through direct consultation with multiple astronauts and the VR Laboratory at NASA's Johnson Space Center in Houston. Real NASA astronaut footage and personal accounts are woven throughout the experience, providing the kind of first-hand guidance that no studio could fabricate. Magnopus's background in Hollywood visual effects and interactive entertainment gives the simulation production values that feel genuinely cinematic.

The experience was later made available on Meta Quest (2019), expanding it from the PC VR headset to standalone use. It has recently also appeared on Steam. Road to VR called it "an impressively detailed view of life in zero gravity" and Space.com covered its release as a significant educational achievement in partnership with NASA.